Webinar: Enzymes: Extracting Biological Insight Using UniProt
This 1-h webinar will introduce the enzyme-related data in UniProt and how to find it.
Registration deadline: 30 May 2024
Date: 06 June 2024
General information
- Time: 06 June 2024, 15:00 CET (09:00 EST) and end around 16:00 CET (10:00 EST).
- Registration deadline: 30 May 2024
- Location: Online
- Fees: Free
Description
Are you struggling to answer a question about proteins, more specifically, enzymes? Unsure whether the information you need is in UniProt? If so, this webinar is for you.
UniProt is the world’s leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information. Enhanced enzyme annotation in UniProtKB is based on Rhea, a comprehensive expert-curated database of biochemical reactions that uses the ChEBI ontology to describe reaction participants.
Starting with a biological question (I.e., Could you refine my list of enzymes to identify the ones with cysteine at the active and/or allosteric sites?), you will explore the different ways of answering it, using UniProt’s advanced query, or SPARQL when the use of UniProt advanced queries is not applicable. Hints on how to extend queries to other biological contexts will also be provided.
Learning outcomes
At the end of the course, the participants are expected to:
- describe the information on enzymes found in UniProt
- use the advanced search to query UniProt for enzyme information
- recognize when the advanced search cannot be used to answer a question
- understand how a SPARQL query is constructed
- execute a SPARQL query to retrieve enzyme data from UniProt
- know where to find help, documentation and get support